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Agamid Adenovirus 1
A variety of adenoviruses
have been identified in reptiles. The most problematic so far is the Agamid adenovirus 1.
Fatal gastroenteritis and hepatitis have been reported
in a variety of lizards, but one of the most commonly affected is the Bearded dragons (Pogona vitticeps). Typical
individuals infected are the young stock and clinical signs presenting can be an acute depression and anorexia. This is quickly
followed by death. Other animals can have a more latent progression of the disease and present as a poor doing stunted individual.
Many animals can have secondary infectious agents present such as Microsporidium or Coccidiosis.
The diagnosis of these conditions
can be difficult. At present Microsporidium requires a histological diagnosis, Coccidia can be found
on a faecal examination. Histopathology can identify the inclusion bodies associated with Adenoviruses. These typically are
basophilic and intranuclear. The liver is a good site to biopsy for a diagnosis. However now there is a PCR available to check
for Adenovirus DNA. Suitable samples to submit include cloacal or oral swabs. These are best sent in a sterile universal.
This is a one step PCR specifically for Agamid Adenovirus 1.
Post mortem examination can reveal multiple haemorrhages and a severe hepatopathy. It is likely the
haemorrhages reflect the severity of the hepatic disease. Histopathological changes can be found in the liver, pancreas, kidney
and intestinal mucosa.
PCR detection
£31.00
Exotic Histology detection on up to 3 tissues £44.00
Exotic Histology detection on 4 - 6 tissues
£61.00
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